Ex Vivo characterization of canine liver tissue viscoelasticity after high-intensity focused ultrasound ablation.

Viscoelasticity Parameters of Hifu Ablated Canine Liver Tissues Ex Vivo

Background: The feasibility of using elasticity imaging techniques for high–intensity–focused–ultrasound (HIFU) ablation monitoring and assessment has been previously demonstrated both in vitro and in vivo (e.g. [1,2]). Nonetheless, effective use of these techniques requires quantitative assessment of the changes in the mechanical properties of the ablated tissue during the treatment process. T...

Potential Strong-hifu-ablation-induced Tissue Damage as Measured by Viscoelastic Characterization of Canine Liver Tissue Post-ablation

Objective: High Intensity Focused Ultrasound (HIFU) has been shown capable of ablating soft tissues in vitro and in vivo. However, mainly due to the lack of knowledge of the exerted radiation force in tissue, mechanical characterization of ablated tissues, particularly at very high HIFU powers, remains largely understudied. This study aims at quantifying the canine liver tissue viscoelastic pro...

Numerical Study for Optimizing Parameters of High-Intensity Focused Ultrasound-Induced Thermal Field during Liver Tumor Ablation: HIFU Simulator

Introduction High intensity focused ultrasound (HIFU) is considered a noninvasive and effective technique for tumor ablation. Frequency and acoustic power are the most effective parameters for temperature distribution and the extent of tissue damage. The aim of this study was to optimize the operating transducer parameters such as frequency and input power in order to acquire suitable temperatu...

Title: Ex Vivo Characterization of Canine Liver Tissue Viscoelasticity Following High Intensity

High intensity focused ultrasound (HIFU) focal spot localization using harmonic motion imaging (HMI).

Several ultrasound-based imaging modalities have been proposed for image guidance and monitoring of high-intensity focused ultrasound (HIFU) treatment. However, accurate localization and characterization of the effective region of treatment (focal spot) remain important obstacles in the clinical implementation of HIFU ablation. Harmonic motion imaging for focused ultrasound (HMIFU) is a HIFU mo...